Background. The IL-33/ST2 axis is involved in humoral immune responses. Method. The concentrations of sera IL-33 and sST2\nin 74 patients and 34 healthy controls (HC) were measured by ELISA. Clinical and laboratory data were examined.The potential\nassociation between sera IL-33 and sST2 and the clinical parameters in IgAN patients were analyzed. Results. No difference was\ndiscovered in IL-33 concentrations between IgAN patients and HCs; however, the sST2 were significantly higher in each stage of\nIgAN progression than in the HC.The concentration of sST2 was positively correlated with IL-33 levels in IgAN patients. Higher\nlevels of sera IL-2, IL-4, IL-10, IL-17A, and IFN-
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